The Research Collection
Key research on issues relating to hypoparathyroidism, hyperparathyroidism and surgery.
Some of these articles will require password entry.
The 5th National Audit Report 2017 from the BAETS Audit, now re-named as the United Kingdom Registry of Endocrine and Thyroid Surgery (UKRETS). David Chadwick, Robin Kinsman & Peter Walton on behalf of BAETS
Management of Hypoparathyroidism: Summary Statement and Guidelines Report #1 from the First International Conference on “The Diagnosis, Management and Treatment of Hypoparathyroidism” held in Florence, Italy May 7–9, 2015Maria Luisa Brandi1 , John P. Bilezikian2 , Dolores Shoback3 , Roger Bouillon4 , Bart Clarke5 , Rajesh V. Thakker6 , Aliya Khan7 , and John T. Potts Jr J Clin Endocrinol Metab p
Effect of Low Vitamin D on Volumetric Bone Mineral Density, Bone Microarchitecture, and Stiffness in Primary Hyperparathyroidism. J Clin Endocrinol Metab. 2016 Mar;101(3):905-13. doi: 10.1210/jc.2015-4218. Epub 2016 Jan 8.Walker MD(1), Nishiyama KK(1), Zhou B(1), Cong E(1), Wang J(1), Lee JA(1), Kepley A(1), Zhang C(1), Guo XE(1), Silverberg SJ(1).
Effects of Parathyroid Hormone Administration on Bone Strength in Hypoparathyroidism.
G-Protein Subunit-α11 Loss-of-Function Mutation, Thr54Met, Causing Familial Hypocalciuric Hypercalcemia Type 2 (FHH2).
European Society of Endocrinology Clinical Guideline: Treatment of chronic hypoparathyroidism in adults
PTH(184) replacement therapy for the treatment of hypoparathyroidism.
Defining the syndromes of parathyroid failure after total thyroidectomy
Pseudohypoparathyroidism type 1a due to a novel mutation in the GNAS gene.
Parathyroid autotransplantation during total thyroidectomy. Results of a retrospective study.
Management of Graves Disease: A Review.
Systematic review and meta-analysis of predictors of post-thyroidectomy hypocalcaemia.Edafe O1, Antakia R, Laskar N, Uttley L, Balasubramanian SP.Br J Surg. 2014 Mar;101(4):307-20. doi: 10.1002/bjs.9384. Epub 2014 Jan 9.
Treatment related morbidity in differentiated thyroid cancer-a survey of clinicians. Edafe O1, Wadsley J, Harrison BJ, Balasubramanian SP.Thyroid Res. 2014 Mar 11;7(1):3. doi: 10.1186/1756-6614-7-3.
Incidence and predictors of post-thyroidectomy hypocalcaemia in a tertiary endocrine surgical unit.Edafe O1, Prasad P, Harrison BJ, Balasubramanian SP.Ann R Coll Surg Engl. 2014 Apr;96(3):219-23. doi: 10.1308/003588414X13814021679753.
Understanding the burden of illness associated with hypoparathyroidism reported among patients in the PARADOX study. Hadker, Eden, Sanders, Lagast, Clarke Endocrine Practice Vol20 No7 July 2014
Impact of postoperative magnesium levels on early hypocalcaemia and permanent hypoparathyroidism after thyroidectomy.Garrahy A1, Murphy MS, Sheahan P.Head Neck. 2014 Dec 9. doi: 10.1002/hed.23937.
Prevalence of hypocalcaemia and its associated features in 22q11·2 deletion syndrome Cheung EN1, George SR, Costain GA, Andrade DM, Chow EW, Silversides CK, Bassett AS.Clin Endocrinol (Oxf). 2014 Aug;81(2):190-6. doi: 10.1111/cen.12466. Epub 2014 May 27.
Prolonged spontaneous normocalcaemia in pseudohypoparathyroidism from resorption of soft tissue calcium deposits: a cautionary tale. Carter EE, Kline G, BMJ Case Rep 2014 Jan 30;2014. pii: bcr2013202729. doi: 10.1136/bcr-2013-202729.
Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the Fourth International Workshop.
Efficacy and safety of recombinant human parathyroid hormone (1-84) in hypoparathyroidism (REPLACE): a double-blind, placebo-controlled, randomised, phase 3 study. Mannstadt M1, Clarke BL2, Vokes T3, Brandi ML4, Ranganath L5, Fraser WD6, Lakatos P7, Bajnok L8, Garceau R9, Mosekilde L10, Lagast H9, Shoback D11,Bilezikian JP12. Lancet Diabetes Endocrinol. 2013 Dec;1(4):275-83. doi: 10.1016/S2213-8587(13)70106-2. Epub 2013 Oct 7.
A protocol for avoidance of post-thryoidectomy hypocalcaemia, results of first 12 months’ audit
Predictors of Hypocalcemia after Thyroidectomy: Results from the Nationwide Inpatient Sample RL. Baldassarre, DC. Chang, KT. Brumund, M.Bouvet. IRSN Surg. 2012;2012:838614
Mini-review: new therapeutic options in hypoparathyroidism.
Normocalcemic primary hyperparathyroidism: A newly emerging disease needing therapeutic intervention
Hypoparathyroidism in the adult: Epidemiology, diagnosis, pathophysiology, target-organ involvement, treatment, and challenges for future research
Synthetic human parathyroid hormone 1-34 replacement therapy : A randomised crossover trial comparing pump versus injection in the treatment of chronic hypoparathyroidism.
The effect of adding PTH(1-84) to conventional treatment of hypoparathyroidism: a randomized, placebo-controlled study. Sikjaer, Reinmark, Rolighed, Heinkendorff, Mosekiilde, Hypoparathyroidism Study Group; J Bone Miner Res2011 Oct;26(10):2358-70. doi: 10.1002/jbmr.470.
Hypocalcaemia after thyroidectomy: the need for improved defenitions
Diagnosis and management of vitamin D deficiency
Long-term treatment of 12 children with chronic hypoparathyroidism: a randomized trial comparing synthetic human parathyroid hormone 1–34 versus calcitriol and calcium. , , , , , J Clin Endocrinol Metab. 2010;95:2680–8.
Parathyroid Disorders and Diseases Altering Calcium Metabolism.
A Practical Approach to Hypocalcaemia in Children
Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the Third International Workshop.
Medical management of asymptomatic primary hyperparathyroidism: proceedings of the Third International Workshop. Khan A, Grey A, Shoback D. J Clin Endocrinol Metab. 2009;94:373–81. doi: 10.1210/jc.2008-1762. [PubMed] [Cross Ref]
Anti-Parathyroid and Anti-Calcium Sensing Receptor Antibodies in Autoimmune Hypoparathyroidism
Diagnosis & Management of Hypocalcaemia: Clinical Review
Unrecognised Severe Hypovitaminosis D
Hypoparathyroidism: Is It Time for Replacement Therapy?
Hypoparathyroidism : Clinical Review
Vitamin D status in postmenopausal women living at higher latitudes in the UK
DiGeorge Syndrome presenting as late onset hypocalcaemia in adulthood
Effects of once versus twice -daily PTH 1-34 therapy in children with HPTH
Dynamic and structural properties of the skeleton in hypoparathyroidism.
Hypoparathyroidism after total thyroidectomy: A prospective study.
Best practice in primary care pathology: review 11.
Vitamin D Deficiency: Clinical Review
Cyclical changes in calcium metabolism across the menstrual cycle in women with premenstrual dysphoric disorder
The impact of single parathyroid gland autotransplantation during thyroid surgery on postoperative hypoparathyroidism: a multicenter study. Transplant Proc.Testini M, Rosato L, Avenia N, et al. 2007;39:225-230.
Withdrawal of alfacalcidol supplements following thyroidectomy: baseline plasma PTH predicts successful outcome
A comparison of corrected serum calcium levels to ionized calcium levels among critically ill surgical patients.
Severe hypocalcaemia after being given intravenous bisphosphonate
Minimally invasive parathyroid surgery
The impact of clinical guidelines on surgical management in patients with thyroid cancer
The impact of surgical technique on postoperative hypoparathyroidism in bilateral thyroid surgery: a multivariate analysis of 5846 consecutive patients
Long-term treatment of hypoparathyroidism: A randomized controlled study comparing parathyroid hormone versus calcitriol and calcium.
Prevention, evaluation, and management of complications following thyroidectomy for thyroid carcinoma. , , . Endocrinol Metab Clin North Am. 2003;32:483–502.
Well-being, mood and calcium homeostasis in patients with hypoparathyroidism receiving standard treatment with calcium and vitamin D
Effect of parathyroid hormone (1–34) on fractures and bone mineral density in postmenopausal women with osteoporosis. , , , et al. N Engl J Med. 2001;344:1434–41.
Genetic ablation of parathyroid glands reveals another source of parathyroid hormone. , , , et al.Nature.2000;406:199–203.
Oestrogen and calcium homeostasis in women with hypoparathyroidism